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п»ї<title>Spongiform encephalopathy or mad cow disease</title>

Spongiform encephalopathy is a lesser known, but equally important type of dementia. When we talk about dementia, we always tend to think of Alzheimer's disease, but there are many other more silent types of dementia that affect thousands of people.
To begin with, it is important to go a little deeper and know the definition of dementia. Dementia is a plurietiological clinical syndrome involving intellectual deterioration from a previous level, usually chronic. This syndrome is not necessarily irreversible or progressive. However, intellectual deterioration implies an impairment of the subject's functional capacities, sufficient to interfere with his or her social and occupational activities.
Focusing on today's topic, spongiform encephalopathy, also known as mad cow disease or Creutzfeldt-Jakob disease (CJD) is a dementia of infectious origin caused by prions. It is degenerative and appears spontaneously or by genetic inheritance. The incidence is one or two cases per 100,000 inhabitants (Vich, 2006).
Causes of CJD As mentioned above, spongiform encephalopathy is of infectious origin. It is caused by prions. A prion is an altered or malformed protein that has the ability to modify similar proteins in our body and cause infections.
The incubation period of the disease can be very long. However, once symptoms begin to appear, the course becomes rapid and progressive. It leads to death in almost 90% of cases within a year of the first symptoms.
This protein affects the brain and nervous system. It causes a multitude of holes in the nervous system, which results in a sponge-like shape. Hence the term "spongiform". Although it is not known with certainty, it is believed that this disease can come from three routes (Vich, 2006):
Ingestion of meat from diseased bovine animals.
Genetic, by mutation in the gene encoding the prion protein, which conditions a disease of autosomal dominant transmission.
Occasionally, iatogenic origin.
"Disease research has advanced so far that it is increasingly difficult to find someone who is completely healthy."
-Aldous Leonard Huxley
Symptoms of spongiform encephalopathySome of the symptoms that can be identified in people with spongiform encephalopathy are:
Depression. Sadness, anhedonia, feeling of being a burden, lack of hope, etc., which cause significant discomfort or loss of
of functionality.
Delusion. It is a false idea or an erroneous interpretation of reality. Kraepelin defines it as a "psychic error which arises from a pathological cause and whose justification and rectification is resistant to logical argumentation".
Hallucination. It is a false perception of objects or events and is sensory in nature. The person feels, smells, hears... something that is not really there or is not happening. Esquirol says of them that they are "sensations really perceived, with no object close to the reach of the senses".
Ataxia. It supposes the loss of coordination in movements, clumsiness or rigidity.
Loss of memory.
Difficulty in speaking.
Difficulty in swallowing.
dementia
Forms of preventionThis disease, like others that course as dementia, has no treatment. Therefore, it is recommended to take preventive measures whenever the authorities deem it necessary:
Active and passive surveillance programs for the rapid detection of affected animals, both on the farm and at the slaughterhouse.
Prohibition of meat and bone meal from mammalian origin. As well as processed animal proteins in feed for animals destined for human consumption.
Veterinary inspections in livestock farms. It is also advisable to monitor warehouses and feed mills for feeding ruminants.
Slaughter of potentially infected animals.
Do not consume meat where there is no guarantee of safety.
However, whenever there is a suspicion of contagion or doubts about the disease, it is advisable to consult a professional for guidance. Health professionals are the only ones who can give us a reliable diagnosis and measures for action.
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